Bradley Wood scored a last-minute equaliser as Lincoln twice fought back to share the spoils with Southport.
Andy Bishop got on the end of a Louis Almond cross to nod the hosts ahead, only for Robbie McDaid to respond immediately for the Imps.
Jamie Allen met a Mike Phenix cross to edge Southport ahead before Terry Hawkridge centred for Wood to head home and earn Lincoln a point.
Lincoln remain 11th in the National League, while Southport are 16th.
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